COMPANY PROFILE

SERICHIM is contract research and manufacturing organization (CRMO) focused in developing chemical and biochemical synthetic methods and processes for fine chemicals and API production. Our analytical competence has been useful to find and validate solutions for safety and environmental remediation problems.

SERICHIM aims to be considered as the “partner of choice” chemical industries to optimize synthetic routes, develop processes and analytical characterization; SERICHIM support its customers with a team of 20 specialists, 1000 m2 labs and three pilot plants.

SERICHIM promotes open innovation by licensing its patents and by knowledge network implementation with customers, universities and other innovation centers.


Operative Structure
Laboratories:

  • 1000 m2 R&D laboratories
  • Bioreactor liquid state fermentation and preparative liquid chromatography
  • Parallel synthesis platform
  • Reaction Calorimetry
  • Fermenter and large scale FPLC
  • Kilolab reactors and unit operations equipment
  • Two Pilot Plants with a capacity from 10 to 500 liter

Analytical Apparatuses:

  • NMR BRUKER Advance 400 Mhz,
  • HPLC-MS X500R QTOF SCIEX mass spectrometry,
  • HS-GC-MS
  • GC
  • HPLC
  • UV-Vis spectrophotometer
  • FT-IR
  • R&D Integrated Center

R&D Integrated Centre
Organic Synthesis Services

  • Studies for synthesis of new molecules
  • Preparation of chemical products from few grams up to hundreds fo kilograms
  • Characterisation of products in terms of quality and physical properties

Analytical Services

  • Validation of analytical methods
  • Preparation and certification of analytical standards
  • Characterization of impurities
  • Problem solving

Process Development

  • Sizing and simulation of unit operations
  • Experimental studies of unit operation performances
  • Measurement of chemical and physical data for risk assessments

Fermentation and Bioprocess Engineering

Upstream processing:

  • Strain development and characterization
  • Formulation of culture broths and fermentation methodology
  • Microbial fermentation in batch/fed-batch bioreactor using diverse gassing strategies

Downstream processing:

  • Expression and purification of peptides, enzymes, proteins and biologics

Biocatalysis:

  • Production and characterization of whole-cell catalysts
  • Cell lysis, enrichment studies, and characterization of biocatalytic activities

Genomic benchmarking for species identification and property rights

Patent analysis and bibliographic studies about chemical topics
Preliminary evaluation of process feasibility and production costs
Preparation of Material Safety Data Sheets

SERICHIM S.r.l. - Piazzale Marinotti 1 - 33050 Torviscosa (UD) - Italy
Tel. +39 0431 381403 - Fax +39 0431 381400 - info@serichim.it
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